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Functions of Arbutin

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Functions of Alpha Arbutin

Arbutin, p-hydroxybenzene-D-glucopyranoside, is a natural active substance derived from green plants. It can be used for diuretics, urinary system anti-infectives, color photography development stabilizer, and also has antitussive effect. Since the 1980s, studies have found that arbutin, as a competitive inhibitor of tyrosinase, can inhibit the activity of the key enzyme tyrosinase in the process of melanin formation, so it has a whitening effect and is not irritating to the skin. Toxic and side effects are small.


Japan's Shiseido Company first applied arbutin in whitening cosmetics. Arbutin is a skin depigmentation component that integrates "green plants, safety and reliability" and "high-efficiency depigmentation". Inhibit the activity of tyrosinase in the skin, block the formation of melanin, and directly combine with tyrosinase to accelerate the decomposition and excretion of melanin, thereby reducing skin pigmentation, removing pigmentation and freckles, and not affecting melanocytes. It produces toxic, irritating, sensitizing and other side effects, as well as bactericidal and anti-inflammatory effects.


Arbutin is used in advanced cosmetics and can be formulated into skin cream, freckle cream, advanced pearl cream, etc. It is a relatively safe and effective whitening raw material popular today, and it is also an ideal skin whitening and freckle-removing active agent in the 21st century. Arbutin is present in many plants such as the whole grass of Saxifrifra stolonifiera (L.) Meerb. chemical synthesis. The preparation method mainly includes organic synthesis method, enzymatic transformation method, plant tissue culture method and natural product extraction method.


At present, the production process of β-arbutin is relatively mature, and there are many reports. The whitening effect of α-arbutin is 10 times better than that of β-arbutin, and it will not inhibit the growth of human cells and has no toxic side effects. Studies have found that α-arbutin has a better therapeutic effect on scars caused by ultraviolet burns, and has better anti-inflammatory, repairing and whitening effects. It is mainly obtained by methods such as plant extraction or biological fermentation. There are few reports about chemical synthesis methods in the literature, and there are fewer methods suitable for industrial production.


Physical and chemical properties and structure

Arbutin, also known as arbutin, is a white needle-like crystal or powder. Extracted from bearberry leaves, it can remove stains and freckles, as well as sterilization and anti-inflammatory effects. Mainly used for the preparation of advanced cosmetics. Arbutin is a natural active substance that can effectively inhibit the activity of biological tyrosinase in the skin, block the formation of melanin, accelerate the decomposition and excretion of melanin, thereby reducing skin pigmentation, removing pigmentation and Freckles are the main active substances in whitening cosmetics at home and abroad. In recent years, with the development of the domestic cosmetics industry, in order to comply with the trend of "returning to nature" in skin care cosmetics, the "green whitening" of natural active substances has become increasingly popular. material, the market demand is expanding.


 

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